Kiani Barnard-Pratt, a senior at Alfred University, has taken significant strides in her biomaterials engineering studies, focusing on 3D printing applications for tissue and bone regeneration. Initially drawn to the field by an interest in prosthetics, her current research project exemplifies the intersection of innovative technology and medical science.
Research Foundations
Barnard-Pratt’s capstone project, titled “Parameter Optimization for 3-D Printing of Sol-Gel-Derived Bioactive Glass,” builds on the pioneering work of alumna Danielle Perry, who recently completed a PhD in materials science and engineering. Perry’s research centered on the development of bioactive glass composites integrated with therapeutic ions, aimed at enhancing tissue repair. This foundational work has set the stage for Barnard-Pratt’s investigation into optimizing material parameters for 3D printing.
The Bioplotter: A Cutting-Edge Tool
Central to Barnard-Pratt’s research is the bioplotter located in the CREATE Center of the McMahon Engineering Building. This advanced equipment, acquired in 2023 through funding from SUNY, allows for the 3D printing of diverse materials, including glass and ceramics. The bioplotter extrudes these materials onto scaffolding, which then undergoes solidification through various methods, such as polymerization and UV exposure.
The versatility of the bioplotter is remarkable. It can print with a range of materials, including plastics and living cells, making it an invaluable asset for biomedical applications. Barnard-Pratt’s work specifically leverages bioactive glass, a material known for its biocompatibility and ability to promote tissue regeneration.
Bioactive Glass in Tissue Regeneration
Bioactive glass is a unique material that interacts with human cells to stimulate growth and healing. Its composition often includes elements like phosphorus and calcium, which facilitate the formation of new bone. In her project, Barnard-Pratt is experimenting with creating scaffold structures that incorporate bioactive glass, which human cells can metabolize to foster tissue regeneration.
The process begins with 3D printing intricate scaffold designs that serve as a framework for tissue growth. Once implanted, these scaffolds slowly degrade, allowing the bioactive glass to release beneficial ions that enhance healing. Barnard-Pratt’s research aims to fine-tune the glass’s degradation rate, ensuring it aligns with the body’s tissue regeneration needs.
Parameter Optimization and Experimental Design
In her capstone, Barnard-Pratt is testing various weight percentages of bioactive glass to determine how these variations affect the printing process and the subsequent degradation of the material. This optimization is crucial because the rate at which bioactive glass breaks down can significantly impact its ability to promote healthy tissue formation.
Her approach involves assessing the uniformity of glass distribution within the scaffolds and its integration into the body. By utilizing the bioplotter effectively, Barnard-Pratt seeks to establish a protocol that maximizes the healing potential of the printed scaffolds.
Collaboration and Mentorship
Barnard-Pratt credits her academic advisors, Tim Keenan and Anthony Wren, for guiding her exploration into tissue regeneration and the potential of bioactive glass. Their mentorship has not only provided her with the necessary technical skills but also inspired her passion for hands-on research in the field.
Through her capstone project, Barnard-Pratt has developed a deeper understanding of the complexities involved in tissue engineering. “I didn’t know tissue regeneration was possible with glass,” she remarked, highlighting her journey from curiosity to expertise.
Future Aspirations
As Barnard-Pratt approaches graduation, she is determined to carve a niche for herself in the biomedical industry, focusing on prosthetics and tissue engineering. She recognizes the relevance of her capstone experience to her future career, particularly in mastering 3D printing technology and its applications in healthcare.
The skills and insights gained from her research will undoubtedly serve as a valuable foundation as she navigates the challenges of the biomedical field.
Key Takeaways
- Kiani Barnard-Pratt is researching 3D printing applications for tissue regeneration at Alfred University.
- Her capstone project builds on the work of Danielle Perry, focusing on optimizing bioactive glass for 3D printing.
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The CREATE Center’s bioplotter enables the printing of complex scaffolds that promote tissue healing.
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Barnard-Pratt’s research emphasizes the importance of material degradation rates in tissue regeneration.
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With guidance from mentors, she is poised to make significant contributions to the biomedical industry after graduation.
In conclusion, Kiani Barnard-Pratt’s work stands at the forefront of innovative tissue engineering. Her research not only advances the field of 3D printing but also holds promise for future medical applications that could transform healing processes. As she prepares to enter the biomedical industry, her contributions will undoubtedly resonate within the realms of prosthetics and regenerative medicine.
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