In the labyrinthine world of Alzheimer’s disease research, a recent study has thrown a spotlight on the enigmatic role of ApoE-ε4, known as the most significant genetic risk factor for late-onset Alzheimer’s. This study has revealed intriguing details about the relationship between apoE4 and amyloid-β, a protein notorious for its association with Alzheimer’s disease. As […]
Tag: affinity
Optimizing Monoclonal Antibody Scaling
In the ever-evolving biotech landscape, the translation of monoclonal antibodies (mAb) from preclinical to clinical settings has emerged as a sophisticated scientific endeavor, hinging on the intricacies of pharmacokinetic target-mediated drug disposition (PK-TMDD) models. This process requires a keen understanding of allometric scaling principles and their underlying assumptions regarding TMDD parameters. The translation of mAb […]
Revolutionizing Drug Discovery with AI-Powered Virtual Screening
Recursion Pharmaceuticals’ stock has experienced a notable surge following the launch of Boltz-2, an advanced AI model. The innovative technology was developed in a collaboration with the Massachusetts Institute of Technology (MIT). Boltz-2 is a groundbreaking biomolecular foundation model capable of predicting molecular structure and binding affinity simultaneously. Its accuracy rivals that of traditional calculations, […]
Affinity Solutions Unveils Fansactions™ Metric for Live Sports Impact
Affinity Solutions introduces Fansactions™, a metric developed through collaborative research with EDO to assess the influence of live sports advertising exposure on consumer behavior. The joint study delves into mid-funnel engagement metrics like brand searches and website visits, as well as lower-funnel outcomes such as QSR purchases. Initial results indicate that incorporating live sports in […]