Using just 1mL of plasma, the Precede Bio platform identified key molecular pathways associated with response and resistance in patients with metastatic breast and prostate cancer treated with sacituzumab govitecan and 177Lu-PSMA-617, respectively. This breakthrough in identifying resistance mechanisms provides crucial insights for personalized treatment strategies, potentially improving patient outcomes and reducing unnecessary side effects. […]
Tag: cancer
Advances in Personalized Cancer Treatment
Cancer survivors are celebrating the progress in personalized treatment through precision medicine, utilizing targeted radiation and customized medication. Dr. Michael Gieske, from St. Elizabeth Healthcare, sheds light on the intricacies of this tailored approach, showcasing how it enhances individual care journeys. With a focus on precision and individual needs, personalized cancer treatment is revolutionizing patient […]
Debunking Turbo Cancer Myths by Makis: A Quack Exposed
The ‘turbo cancer’ myth, propagated by Dr. William Makis, a delicensed radiologist turned oncologist, has been debunked. Makis falsely claims that COVID-19 vaccines cause ‘turbo cancers,’ which are supposedly faster-growing and malignant. Despite lacking evidence, he promotes unproven treatments like ivermectin, fenbendazole, and mebendazole for cancer. This exposes the dangers of misinformation in cancer care […]
Ultrasensitive DNA Biosensor for Fusobacterium Detection
Fusobacterium nucleatum, a bacterium associated with colorectal cancer, contains the fadA gene, a valuable early diagnostic biomarker. The study highlights the integration of CRISPR/Cas12a system and an improved electrochemiluminescence (ECL) biosensor for ultrasensitive detection. CRISPR/Cas-based sensors face challenges like probe entanglement and reduced enzyme efficiency, but ECL offers superior spatiotemporal control and background noise reduction, […]
AI Advances Long-Read Sequencing in Clinical Applications
Long-read sequencing, a cutting-edge technology in genomics, is being propelled into clinical use with the help of artificial intelligence (AI). Researchers acknowledge support from various funding sources, including EMBL, Wellcome Trust, and several other organizations. Access to crucial patient data was facilitated through Genomics England’s National Genomic Research Library. Carolin Sauer, from the Cortes-Ciriano group […]
European Biotech Trends for 2025 and Beyond
In 2016, the International Consortium for Personalised Medicine (ICPerMed) was established by over 30 European members in collaboration with the European Commission. IHU PRISM, the first national center for precision medicine in oncology in France, emerged from a partnership between ICPerMed and Institut Hospitalo-Universitaire. This initiative, focusing on cancer care, received a significant €30 million […]
Personalis’ NeXT Personal® Predicts Cervical Cancer Recurrence Risk
Personalis’ NeXT Personal® test shows promise in predicting cervical cancer recurrence risk. The innovative test aims to detect small traces of ctDNA, monitor response to therapy, and predict clinical outcomes. This groundbreaking analysis presented at ASCO highlights the potential of NeXT Personal to impact cancer care and management, offering early detection and personalized treatment strategies. […]
Promising Results of CAR T Cell Therapy for Tough Tumours
A recent trial involving 156 participants with advanced gastric or gastro-oesophageal junction cancer, resistant to previous treatments, showed positive outcomes with Satri-cel. This cell therapy, administered up to 3 times alongside immune cell depletion, demonstrated efficacy in individuals positive for CLDN18.2. The control group received standard therapies like nivolumab, paclitaxel, or rivoceranib. Read more from […]
Utilizing Medical Marijuana to Combat Cancer
Medical marijuana, particularly cannabinoids, has shown promise in alleviating chemotherapy-induced nausea and vomiting (CINV), which can hinder nutrition and treatment adherence. By interacting with the endocannabinoid system in the brain, cannabinoids can reduce nausea and increase appetite. Clinical trials, including those highlighted in a National Cancer Institute review, have demonstrated that cannabinoids are at least […]
First FDA-Authorized AI Platform for Breast Cancer Prediction
Clairity marks a significant advancement in women’s health by becoming the initial FDA-authorized AI platform for predicting breast cancer. This milestone showcases the integration of cutting-edge technology in the realm of healthcare, offering a promising tool for early detection and personalized treatment. Leveraging artificial intelligence, Clairity sets a precedent for more accurate and efficient breast […]
Long Noncoding RNAs & Microproteins in Cancer Modulation
Long noncoding RNAs (lncRNAs) and microproteins play crucial roles in either promoting or inhibiting cancer development. In a recent study, researchers identified a microprotein named MIAC, derived from noncoding RNAs, which showed a significant impact on patient survival in head and neck squamous cell carcinoma. Further analysis revealed MIAC’s involvement in the progression of multiple […]
iTeos Biotech Closure Impacts Cancer Therapeutics Sector
iTeos, a Watertown-based biotech company, announced its shutdown, mirroring a trend in the industry. This decision coincided with Keros Therapeutics’ discontinuation of a high blood pressure drug candidate, resulting in substantial layoffs. With Keros reducing its workforce by 45%, the aftermath leaves the company with only 85 employees, highlighting the challenges faced by biotech firms […]
Personalized Prostate Cancer Care: Genetic Testing and PARP Inhibitors
Prostate cancer treatment is not a one-size-fits-all approach. Factors like patient preference, medical history, and genetic testing play crucial roles in guiding personalized care. Dr. Kristen Scarpato highlights the importance of considering genetic testing to tailor treatments for each individual patient, ensuring a more targeted and effective approach to managing prostate cancer. Read more about […]
Developing UAE’s First Homegrown Cancer Drug
In the pursuit of creating the UAE’s inaugural homegrown cancer drug, Insilico’s lead candidate, Rentosertib, exhibited positive outcomes in a Phase IIa trial for idiopathic pulmonary fibrosis. Rentosertib displayed promising safety, tolerability, and early efficacy signals, showcasing potential as a breakthrough treatment option for this serious lung disease characterized by lung scarring. Read more about […]
Revolutionizing Cancer Care: Digital Tumors in Precision Oncology
Researchers at University of California San Diego have received a $23.6 million award from ARPA-H to develop a groundbreaking approach for selecting cancer treatments. The project, titled ‘Dynamic Digital Tumors for Precision Oncology,’ aims to transform cancer care with AI-powered tools that predict therapy outcomes and tumor evolution. These Drug Recommender Engines (DREs) will enhance […]
Innovative Bioprinter Creates Advanced Wound Patch Technology
Vital3D, based in Vilnius, Lithuania, utilizes a cutting-edge laser-based bioprinting platform to replicate complex tissue structures. CEO Vidmantas Šakalys aims to revolutionize organ creation, starting with 3D-printed kidneys to address the impact of urinary cancer. The company’s pioneering technology offers promising advancements in bioprinting for medical applications. Read more about this — techtimes.com
Financial Impact of Oncology Biosimilars on Different Patient Populations
A recent study examined the financial burden of cancer care on different patient populations, revealing varying average annual costs and prescription spending. Uninsured patients topped the list with an average annual cost of $78,439, followed by Medicare patients at $67,979. VA/TRICARE patients had moderate costs but higher prescription spending at $56,619 and $16,758, respectively. Medicaid […]
AVEO Oncology Showcases Three Posters at ASCO 2025 Meeting
In a significant development at the ASCO 2025 Annual Meeting, AVEO Oncology, a subsidiary of LG Chem Life SciencesUSA, Inc., presented three posters highlighting their commitment to advancing oncology treatments. AVEO, known for its focus on delivering innovative medicines for cancer patients, currently offers FOTIVDA®(tivozanib) for advanced renal cell carcinoma treatment in the U.S. The […]
Enhancing Colon Cancer Survival with Atezolizumab and Chemo
A groundbreaking study has shown that combining atezolizumab with chemotherapy can significantly improve survival rates in patients with colon cancer. This innovative approach raises important questions about the potential for reducing the intensity of chemotherapy or even eliminating it altogether in future treatment regimens. By exploring the efficacy of chemo-free protocols, researchers aim to find […]
Bristol Myers Squibb and BioNTech Partner on $11B Cancer Immunotherapy Deal
In a groundbreaking move, Bristol Myers Squibb and BioNTech have announced a strategic partnership to co-develop and co-commercialize BioNTech’s next-generation cancer immunotherapy, BNT327, across various solid tumor types. This collaboration involves a staggering $11.1 billion agreement, with both companies sharing development and manufacturing costs as well as global profits and losses. Dr. Ugur Sahin, CEO […]
Improved Long-Term Survival with Immunotherapy and Chemotherapy before Lung Cancer Surgery
Groundbreaking research revealed that combining immunotherapy with chemotherapy before lung cancer surgery leads to significantly better long-term survival rates. In a clinical trial involving 358 patients with resectable non-small cell lung cancer, the addition of the anti-PD-1 immunotherapy drug nivolumab to standard chemotherapy resulted in remarkable outcomes. Published in the prestigious New England Journal of […]
AI-based urine test for prostate cancer shows success in clinical trial
PanGIA Biotech’s groundbreaking AI-based urine test for prostate cancer has achieved significant success in a recent clinical trial, marking a major milestone in the field of biotechnology. The test, designed to provide accurate and early detection of prostate cancer, has demonstrated promising results, offering potential benefits for patients and healthcare providers alike. This innovative technology […]
iTeos Ceases Operations in Watertown Biotech Sector
In a significant development for the biotech industry, iTeos has announced the closure of its operations in Watertown. This news comes amidst a series of setbacks for biotech companies, with Keros Therapeutics also recently ending the development of a drug candidate. The decision by iTeos is expected to have implications for the local biotech community […]
STX-001 mRNA Therapeutics Shows Promise in Treating Advanced Solid Tumors
In a groundbreaking development, Strand Therapeutics has revealed the initial Phase 1 data for STX-001 in patients with advanced solid tumors. This mRNA therapeutic aims to address the urgent need for new treatment options in patients who are resistant to immune checkpoint inhibitors. By delivering localized IL-12 expression to activate the tumor microenvironment and stimulate […]
Hope for Rare Cancer Patient: TCR-T Cell Therapy Trial
In a groundbreaking clinical trial, a patient with a rare form of cancer is finding hope through TCR-T Cell Therapy. This innovative immunotherapy approach, conducted through a collaboration between Memorial Cancer Institute and Moffett Cancer Center, involves modifying the patient’s T-cells to target specific proteins in cancer cells. By harnessing the power of the body’s […]
Tecentriq and lurbinectedin combo improves survival in small cell lung cancer
Exciting news has emerged from the Phase III IMforte study, showcasing the positive impact of combining Roche’s Tecentriq with lurbinectedin for first-line maintenance treatment in extensive-stage small cell lung cancer (ES-SCLC). The data revealed a remarkable 46% reduction in the risk of disease progression or death, along with a 27% decrease in the risk of […]
Fiber’s Impact on Immunotherapy in Cancer Treatment
0 Exciting research unveiled at the 2025 American Society of Clinical Oncology Annual Meeting reveals the potential of a fiber-rich, whole-foods-based diet in enhancing outcomes for patients undergoing immunotherapy for cancer, particularly in melanoma care. This innovative approach not only holds promise for improving patient results but also presents a cost-effective and widely applicable strategy, […]
ASCO 2025 Day 3: Genentech’s Innovative Booth Food Steals the Show
As the ASCO 2025 conference enters its third day, Genentech continues to impress attendees with its unique approach to booth food. Known for their iconic cookies, this year Genentech introduces a new treat: s’mores made with Genentech-branded marshmallows toasted with a blowtorch. While delicious, attendees are advised to beware of the messy nature of these […]
Barriers to CAR T-Cell Therapy in Myeloma
Recent discussions among oncologists in West Virginia highlighted the challenges hindering the widespread use of Chimeric Antigen Receptor (CAR) T-cell therapy in patients with relapsed/refractory multiple myeloma. Despite the therapy’s availability, social and logistical barriers prevent many eligible patients from accessing this innovative treatment option. Dr. Konstantinos Sdrimas, an expert in medical oncology, emphasized the […]
Improving Cancer Stem Cell Therapy Delivery
TargaZyme, a biotech company, is on a mission to revolutionize cancer treatment by enhancing the delivery of stem cells to diseased organs. CEO Koh is looking to bring this innovative technology to Singapore, aiming to benefit patients in the region. Collaborating with cord-blood banks in Asia, TargaZyme is in the process of selecting the optimal […]
Defying Grim Prognosis with Cancer Stem Cells in Therapy
In a remarkable feat, patients are defying grim prognoses and celebrating ‘cancerversaries’ thanks to innovative therapies targeting cancer stem cells. Allogeneic transplant procedures, once associated with a 30-40% mortality rate, have evolved to include four-drug cocktails combining chemotherapy and immunotherapies. Dr. Hashmi reflects on advancements in treating multiple myeloma, emphasizing deep and durable remissions achievable […]
University of Houston Secures Funding for Cancer Biomarker Facility Launch
In a groundbreaking development, the University of Houston has secured $3M to establish a state-of-the-art Cancer Immunotherapy Biomarker Core facility. This cutting-edge facility is set to revolutionize biomarker discovery, enhance immunotherapy targeting, and bolster research capabilities throughout Texas. By boosting the state’s standing in cancer research, this initiative promises to drive advancements in patient outcomes […]
Efficacy of New Antibody-Drug Conjugate in CD123-Positive BPDCN Patients
A recent global multi-center trial has demonstrated the effectiveness of a new antibody-drug conjugate in treating CD123-positive BPDCN, a rare form of cancer. The study enrolled 84 adult patients, including 33 newly diagnosed cases and 51 patients with relapsed or refractory BPDCN. Patients received the therapy intravenously in a 21-day cycle, showing promising results in […]
Pharma breakthrough with AbbVie’s ADC in solid tumors
In a significant development, AbbVie’s ADC has showcased its potential to revolutionize solid tumor treatment. Daiichi Sankyo and AstraZeneca are gearing up to unveil phase 3 clinical results for their highly anticipated ADC Enhertu at the upcoming American Society of Clinical Oncology conference. Having already received approval for multiple cancer indications, Enhertu made history as […]
Utilizing Medical Marijuana in Cancer Treatment
Source: https://www.mercurynews.com/2025/06/02/all-the-ways-medical-marijuana-helps-fight-cancer/ Recent studies have highlighted the various ways in which medical marijuana, specifically cannabinoids, can aid in the fight against cancer. One of the earliest FDA-approved uses of THC was in the drug dronabinol, which helps combat chemotherapy-induced nausea and vomiting (CINV). These symptoms not only cause discomfort but can also impact nutrition and […]
Impact of Weight on Cancer Risk and Potential Role of Blockbuster Drugs
Source: https://news.search.yahoo.com/search;_ylt=Awrheq_fdj5o7QEAFlJXNyoA;_ylu=Y29sbwNiZjEEcG9zAzEEdnRpZAMEc2VjA3BpdnM-?p=cancer&fr2=piv-web Recent studies have shown a correlation between excess body weight and an increased risk of certain types of cancer. This has prompted researchers to investigate the potential role of popular drugs like Wegovy, Ozempic, and Zepbound in cancer prevention. Could these blockbuster medications hold the key to reducing the incidence of cancer in […]
Stanford professor teaches life lessons amid terminal cancer diagnosis
Source: https://www.cbsnews.com/news/stanford-professor-terminal-cancer-course/ Amidst a terminal cancer diagnosis, a Stanford professor transforms his experience into a powerful class on life, death, and hope. This unique approach not only sheds light on the struggles of battling cancer but also offers a profound perspective on the human experience. Through this inspiring journey, the professor aims to impart valuable […]
