Tag: CancerResearch

The Tumor Microenvironment: Why the Real Action Happens off-Screen

1 A quick scene-setter (coffee optional) Cancer biologists like to call the tumor a “mass.” In reality it behaves more like Times Square on New Year’s Eve: a jostling crowd of tourists (immune cells), cops (fibroblasts), food trucks (blood vessels), pickpockets (cancer-associated macrophages) and the giant LED billboards of cytokines blaring contradictory instructions. That carnival […]

TCR-T Therapy: Tumor-Sniper Tech for the Next Oncology Revolution

1 If CAR-T was the proof-of-concept that living drugs can wipe out blood cancers, TCR-T is the sequel that tries to take the same logic into the vastly harder terrain of solid tumors. Chimeric antigen receptors recognise intact surface proteins; engineered T-cell receptors read short peptide fragments presented on HLA molecules, letting them “see” the […]