Vaccines and Antibiotic Resistance: Evidence and Gaps

A report summarizes findings from 11 research projects funded by Wellcome to address critical evidence gaps on vaccines and AMR, especially in low- and middle-income countries. In 2024, a World Health Organization study projected that vaccines could prevent over 500,000 deaths from drug-resistant infections annually, leading to significant cost savings and a reduction of 2.5 billion antibiotic doses needed for treatment. The projects examined real-world data showcasing how vaccines can combat AMR across various pathogens, environments, and research methodologies.

These findings underscore the vital role vaccines play in mitigating antibiotic resistance and saving lives globally. The potential impact of vaccines in averting deaths and reducing healthcare costs is substantial, highlighting the urgent need for continued research and investment in vaccine development. With the promise of billions in savings and billions of antibiotic doses spared annually, prioritizing vaccination strategies can significantly contribute to the fight against AMR and promote sustainable healthcare practices.

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