1 Contract Development and Manufacturing Organizations (CDMOs) specializing in fermentation and biomolecule production face complex contamination risks that can jeopardize batch integrity, regulatory compliance, and product efficacy. While spore-forming bacteria (sporocidal challenges) are a well-known concern, contamination threats extend far beyond spores. These risks, if left unmanaged, can result in costly recalls, compromised therapeutic potency, […]
Tag: Fermentation Technology
How Can I Push Recombinant Casein Titers Above 5 g/L in E. coli?
1 Producing recombinant casein in E. coli at titers above 5 g/L is an ambitious but increasingly feasible goal for biopharma researchers and synthetic biology startups. As interest in alternative proteins, functional food ingredients, and milk analogs grows, optimizing microbial hosts like E. coli for high-yield recombinant casein production has become a hot topic across […]
Solid-State Fermentation: The Comeback Tech
1 Introduction: Fermentation’s Forgotten Twin In the age of sleek bioreactors, precision fermentation, and gene-edited microorganisms, it’s easy to overlook one of the oldest and most effective fermentation techniques: solid-state fermentation (SSF). Yet, SSF is making a powerful comeback—reimagined for today’s needs in food tech, alternative proteins, biomanufacturing, and even pharmaceuticals. Unlike submerged fermentation (SmF), […]
Koji-Based Protein: The Future of Meat
1 Introduction: A New Dawn for Meatless Innovation Imagine a savory steak or a smoky slice of bacon crafted not from animals, but from mold. Sounds unappetizing? Think again. Thanks to recent advancements in fermentation technology, koji-based meat alternatives are emerging as a game-changing force in the alternative protein industry. What was once an ancient […]
Brewing the Future: Fermentation and the Rise of Alternative Proteins
1 Imagine biting into a juicy burger, enjoying creamy cheese, or savoring succulent seafood—all produced without animals. This isn’t science fiction; it’s the exciting reality of alternative proteins, powered by fermentation technologies. Fermentation isn’t just for beer and bread anymore; it’s revolutionizing how we produce sustainable, nutritious, and delicious protein sources. Welcome to the bold […]