Telomeres, the protective caps of chromosomes, shorten during cell division, a process accelerated by stress. Once telomere length drops below a critical threshold, cell death and senescence occur. Senescent cells, unable to divide, continue to secrete pro-inflammatory molecules, linking accelerated telomere shortening to a shorter lifespan and diseases like coronary artery disease, atherosclerosis, type 2 […]
Tag: autoimmune diseases
Unveiling Immunocore Holdings: Analyst Reviews Illuminate Innovations
Immunocore Holdings PLC, a commercial-stage biotechnology company, utilizes its ImmTAX platform to advance a diverse pipeline across various therapeutic areas. These include clinical stage programs in oncology and infectious disease, pre-clinical programs in autoimmune disease, and earlier pre-clinical programs spanning three therapeutic areas. The company’s lead product, KIMMTRAK, targets unresectable or metastatic uveal melanoma (mUM), […]
Advancing Autoimmune Disease Research
The Global Autoimmune Institute collaborates with top research institutions to drive innovation in autoimmune disease science. From early immune signaling to groundbreaking therapies, we provide evidence-based information to patients and caregivers through digital tools and educational resources. By integrating research, treatment, and support, we aim to create a future where autoimmune diseases are preventable, treatable, […]
Rise of Autoimmune Diseases in Expectant Mothers
Recent research from the University of Birmingham reveals a significant increase in autoimmune conditions among pregnant women since the turn of the millennium. This groundbreaking study, the first of its kind, examined a wide spectrum of autoimmune diseases that predominantly impact women. Previous studies have indicated a general rise in autoimmune disorders, making these findings […]
Autoimmunity and Pathogenesis: A Complex Interplay
The immune system’s protective role can backfire with autoimmunity, where it mistakenly attacks the body’s own cells. This phenomenon, known as autoimmunity, leads to a spectrum of diseases ranging from life-threatening organ failure to subtle shifts in biomarker expression without immediate symptoms. Understanding the interplay between autoimmunity and pathogenesis is crucial for developing effective treatments […]
