Zwitterionic nanoparticles bypass immune surveillance to stimulate antigen-specific immune responses while reducing unwanted immune activation. Research shows that PCB-containing lipid nanoparticles (PCB-LNPs) offer improved transfection efficiency and safety compared to PEG-based LNPs. PCB-LNPs mitigate the accelerated blood clearance effect observed with PEG-LNPs, allowing for repeated administration without loss of efficacy. This innovation paves the way […]