A team at NUS led by Assistant Professor Andy Tay has unveiled a breakthrough in gene delivery for cancer therapy. The novel technique, NExT, can efficiently deliver genetic material into over 14 million immune cells in a single run, including challenging cell types like gamma-delta T cells, dendritic cells, and natural killer cells, crucial for developing alternative immune cell therapies. This innovation holds significant promise for advancing cancer treatment by enhancing the effectiveness of targeted gene therapies and immunotherapies.
This groundbreaking development opens up new possibilities in cancer therapy, offering a potential avenue for personalized treatments tailored to individual patients. By successfully transfecting a wide range of immune cells, including those traditionally hard to engineer, NExT could pave the way for more precise and potent cancer immunotherapies. With further research and refinement, this gene delivery breakthrough has the potential to revolutionize the field of cancer treatment, improving patient outcomes and quality of life.
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